SCHEMBL2808423

SCHEMBL2808423

O=C(O)c1c(-c2ccccc2)oc(-c2ccccc2)c1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 4/20 0.55
ALDH1A1 P00352 5/20 0.50
HPGD P15428 4/20 0.50
KDM4E B2RXH2 4/20 0.50
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 3/20 0.46
MAPK1 P28482 1/20 0.46
RECQL P46063 1/20 0.46
PTPN1 P18031 2/20 0.46
RXRA P19793 2/20 0.45
RXRB P28702 2/20 0.45
PDE4A P27815 1/20 0.43
RXRG P48443 1/20 0.42
NR4A1 P22736 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylmalonic Acid SCHEMBL27562489 0.87 ALDH1A1 (0.51) NR4A2ALDH1A1HPGDKDM4ERAB9A
SCHEMBL5579331 0.80 KDM4E (0.57) ALDH1A1HPGDKDM4ERAB9ANPC1
SCHEMBL21808985 0.78 HTT (0.68) ALDH1A1HPGDKDM4ERAB9ANPC1
SCHEMBL28265156 0.78 MAPT (0.51) NR4A2ALDH1A1HPGDKDM4ERAB9A
SCHEMBL9822648 0.77 PDE4A (0.53) ALDH1A1HPGDKDM4ERAB9ANPC1
SCHEMBL6527669 0.76 ALDH1A1 (0.69) ALDH1A1HPGDKDM4ERAB9ANPC1
SCHEMBL31456561 0.73 ALDH1A1 (0.66) NR4A2ALDH1A1HPGDKDM4EMEN1
SCHEMBL3446771 0.72 LMNA (0.52) ALDH1A1HPGDKDM4ERAB9ANPC1
SCHEMBL2846662 0.72 LMNA (0.52) ALDH1A1HPGDKDM4ERAB9ANPC1
SCHEMBL5098755 0.71 NR4A2 (1.00) NR4A2ALDH1A1HPGDKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431732-B Polyether polyurethane foamed elastomer 大使涂料(安徽)有限公司 2025-04-22 CN claimed
CN-119431732-A Polyether polyurethane foaming elastomer and preparation method thereof 大使涂料(安徽)有限公司 2025-02-14 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-119431732-B Polyether polyurethane foamed elastomer 大使涂料(安徽)有限公司 2025-04-22 CN disclosed
CN-119431732-A Polyether polyurethane foaming elastomer and preparation method thereof 大使涂料(安徽)有限公司 2025-02-14 CN disclosed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
CN-102405039-A Cosmetic or dermatological composition comprising a polymer containing linking groups, and cosmetic treatment method OREAL 2012-04-04 CN disclosed
CN-102325518-A Cosmetic or pharmaceutical composition comprising a polycondensate, polycondensate and method of cosmetic treatment OREAL 2012-01-18 CN disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed
CN-101347389-A Cosmetic or pharmaceutical composition comprising a condensation polymer, cosmetic treatment method, condensation polymer and preparation method OREAL (FR) 2009-01-21 CN disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 NR4A2 4683/4885ALDH1A1 1901/4885HPGD 311/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB NR4A2 4570/4885ALDH1A1 4765/4885HPGD 3660/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA NR4A2 4130/4885ALDH1A1 1510/4885HPGD 826/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA NR4A2 3930/4885ALDH1A1 448/4885HPGD 2278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.