Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29340646 | 0.75 | BAZ2B (0.40) | MAP2K2MAP2K1 | |
| SCHEMBL22980995 | 0.70 | HDAC6 (0.33) | HDAC6MAP2K2MAP2K1 | |
| SCHEMBL26237165 | 0.70 | HDAC6 (0.33) | HDAC6 | |
| SCHEMBL29911786 | 0.68 | HDAC6 (0.31) | HDAC6MAP2K2MAP2K1WDR5 | |
| SCHEMBL20606256 | 0.68 | BRD4 (0.45) | MAP2K2MAP2K1WDR5 | |
| SCHEMBL20606244 | 0.67 | MAP2K1 (0.47) | MAP2K2MAP2K1WDR5 | |
| SCHEMBL20606084 | 0.66 | MAP2K1 (0.47) | MAP2K2MAP2K1WDR5 | |
| SCHEMBL27867751 | 0.63 | IRAK4 (0.36) | — | |
| SCHEMBL28223520 | 0.62 | HRAS (0.36) | — | |
| SCHEMBL28026875 | 0.61 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195965-A | The inhibitor that WDR5 protein-protein combines | 普罗佩纶治疗公司 | 2019-01-11 | — | — | CN | claimed |
| CN-109195965-A | The inhibitor that WDR5 protein-protein combines | 普罗佩纶治疗公司 | 2019-01-11 | — | — | CN | disclosed |