SCHEMBL29340646

SCHEMBL29340646

Cn1cc(NC=O)c(Cl)cc1=O

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BAZ2B Q9UIF8 1/20 0.40
BAZ2A Q9UIF9 1/20 0.40
MAP2K2 P36507 1/20 0.37
MAP2K1 Q02750 1/20 0.37
GAA P10253 2/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAOB P27338 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
ATAD2 Q6PL18 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28265604 0.75 HDAC6 (0.32) MAP2K2MAP2K1
SCHEMBL7529082 0.68 MAOB (0.40) TDP1MAOB
SCHEMBL15550000 0.67 BAZ2B (0.45) BAZ2BBAZ2AMAP2K2MAP2K1ATAD2
SCHEMBL28223520 0.66 HRAS (0.36) POLB
SCHEMBL27467128 0.64 ADORA2A (0.37) POLB
SCHEMBL28026875 0.64 ALDH1A1 (0.40) POLB
SCHEMBL2088762 0.64 RAB9A (0.46) GAAPOLB
SCHEMBL31133035 0.63 BAZ2B (0.69) BAZ2BBAZ2AMAP2K2MAP2K1GAA
SCHEMBL31574401 0.63 BAZ2B (0.45) BAZ2BBAZ2AMAP2K2MAP2K1TDP1
SCHEMBL30132193 0.63 CA1 (0.50) POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400497-A1 3CLPRO PROTEASE INHIBITOR Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) 2024-07-17 EP disclosed