SCHEMBL28265657

SCHEMBL28265657

NCCNCCNn1cnc2c(N)ncnc21

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
ADCY1 Q08828 1/20 0.48
ADORA2A P29274 10/20 0.44
ADORA1 P30542 6/20 0.44
PI4KA P42356 5/20 0.44
PI4K2B Q8TCG2 5/20 0.44
PI4K2A Q9BTU6 5/20 0.44
PI4KB Q9UBF8 5/20 0.44
GSK3B P49841 1/20 0.43
ADORA2B P29275 3/20 0.42
AHCY P23526 1/20 0.42
ADORA3 P0DMS8 1/20 0.41
ADCY5 O95622 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29138713 0.74 ADORA2A (0.50) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL22399264 0.73 ADORA2A (0.56) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL9120 0.72 ADORA2A (0.59) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL29087571 0.71 ALDH1A1 (0.79) ALDH1A1ADCY1ADORA2AADORA1PI4KA
SCHEMBL48453 0.71 ADORA2A (0.50) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL20208091 0.69 ADORA2A (0.56) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL67131 0.68 ADORA2A (0.74) ALDH1A1ADCY1ADORA2AADORA1PI4KA
SCHEMBL5033136 0.67 ADORA2A (0.73) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL28601746 0.67 ADORA2A (0.49) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL9621206 0.67 GSK3B (0.50) ALDH1A1ADORA2AADORA1PI4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180707-B Fluorescent probe for detecting xanthine and preparation method and application thereof 辽宁大学 2020-05-12 CN disclosed
CN-109180707-A Fluorescence probe and its preparation method and application for detecting xanthine 辽宁大学 2019-01-11 CN disclosed