SCHEMBL29138713

SCHEMBL29138713

C#CCNn1cnc2c(N)ncnc21

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 10/20 0.50
ADORA1 P30542 7/20 0.50
PI4KA P42356 6/20 0.50
PI4K2B Q8TCG2 6/20 0.50
PI4K2A Q9BTU6 6/20 0.50
PI4KB Q9UBF8 6/20 0.50
ADORA2B P29275 3/20 0.48
AHCY P23526 4/20 0.47
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
GSK3B P49841 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28004916 0.83 ADORA2A (0.58) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL9120 0.77 ADORA2A (0.59) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL31360519 0.76 ADORA2A (0.50) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL19748698 0.76 ADORA2A (0.50) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL22399264 0.75 ADORA2A (0.56) ADORA2AADORA1PI4KAPI4K2BPI4K2A
Hydrochloric Acid SCHEMBL26629004 0.74 ALDH1A1 (0.62) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL20208091 0.74 ADORA2A (0.56) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL27524728 0.74 ADORA2A (0.59) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL28265657 0.74 ALDH1A1 (0.48) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL3957296 0.73 AHCY (0.66) ADORA2AADORA1PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115867670-A Base-modified nucleotides as substrates for TDT-based enzyme nucleic acids 伊鲁米纳新加坡有限公司 2023-03-28 CN disclosed