Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.79 |
| ▸ | TGM2 | P21980 | 1/20 | 0.78 |
| ▸ | KRAS | P01116 | 8/20 | 0.70 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.69 |
| ▸ | HINT1 | P49773 | 1/20 | 0.65 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.65 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.65 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.65 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.64 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.64 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.64 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513028 | 0.95 | TGM2 (0.80) | NT5ETGM2KRASFUT5HINT1 | |
| SCHEMBL8202050 | 0.95 | NT5E (0.83) | NT5ETGM2KRASFUT5HINT1 | |
| SCHEMBL851357 | 0.94 | TGM2 (0.85) | NT5ETGM2KRASFUT5HINT1 | |
| SCHEMBL29429843 | 0.94 | TGM2 (0.85) | NT5ETGM2KRASFUT5HINT1 | |
| SCHEMBL18769114 | 0.94 | TGM2 (0.85) | NT5ETGM2KRASFUT5HINT1 | |
| SCHEMBL21067722 | 0.94 | TGM2 (0.85) | NT5ETGM2KRASFUT5HINT1 | |
| SCHEMBL23969756 | 0.92 | TGM2 (0.82) | NT5ETGM2KRASFUT5P2RX3 | |
| SCHEMBL80058 | 0.92 | TGM2 (0.82) | NT5ETGM2KRASFUT5P2RX3 | |
| SCHEMBL17072523 | 0.92 | TGM2 (0.82) | NT5ETGM2KRASFUT5P2RX3 | |
| SCHEMBL18775378 | 0.92 | TGM2 (0.82) | NT5ETGM2KRASFUT5P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207891-A2 | MATERIALS AND METHODS FOR THE GENERATION OF TRANSCRIPTS COMPRISING MODIFIED NUCLEOTIDES | Archemix Corp. (US) | 2010-07-21 | — | — | EP | disclosed |
| WO-2008078180-A2 | MATERIALS AND METHODS FOR THE GENERATION OF TRANSCRIPTS COMPRISING MODIFIED NUCLEOTIDES | ARCHEMIX CORP. (US) | 2008-07-03 | — | — | WO | disclosed |