SCHEMBL2826608

SCHEMBL2826608

COC(=O)CN1CCOCC1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.55
HSD17B10 Q99714 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
TSHR P16473 2/20 0.53
ALOX15 P16050 2/20 0.53
GLA P06280 1/20 0.51
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 3/20 0.47
POLB P06746 2/20 0.47
GAA P10253 1/20 0.47
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HPGD P15428 1/20 0.45
TP53 P04637 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28036233 0.98 KDM4E (0.53) KDM4EHSD17B10SMN1; SMN2TSHRALOX15
SCHEMBL12534284 0.88 GLA (0.45) KDM4EHSD17B10SMN1; SMN2TSHRALOX15
SCHEMBL717374 0.86 KDM4E (0.50) KDM4EHSD17B10SMN1; SMN2TSHRALOX15
SCHEMBL70778 0.84 TSHR (0.46) KDM4EHSD17B10SMN1; SMN2TSHRGLA
SCHEMBL1133592 0.84
SCHEMBL12379861 0.84 TSHR (0.46) KDM4EHSD17B10SMN1; SMN2TSHRGLA
SCHEMBL28330001 0.83 HSD17B10 (0.59) KDM4EHSD17B10SMN1; SMN2TSHRALOX15
SCHEMBL26270951 0.82 HSD17B10 (0.54) KDM4EHSD17B10SMN1; SMN2TSHRALOX15
SCHEMBL28738942 0.80
SCHEMBL65441 0.80 ALDH1A1 (0.50) KDM4ESMN1; SMN2TSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113321269-A Method for effectively separating organic matters in high-salinity wastewater 中国科学院过程工程研究所 2021-08-31 CN claimed
US-20260076982-A1 Prodrugs of Cannbidiol [CBD]-Type Phytocannabinoids and a Process for Preparation Thereof COUNCIL SCIENT IND RES (IN) 2026-03-19 US disclosed
EP-4676923-A1 BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS Cancer Research Technology Limited (GB) 2026-01-14 EP disclosed
EP-4660703-A2 METAL-CONTAINING FILM PATTERNING PROCESS Shin-Etsu Chemical Co., Ltd. (JP) 2025-12-10 EP disclosed
US-20250372377-A1 METAL-CONTAINING FILM PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-12-04 US disclosed
US-20250296912-A1 AFFINITY ILLUDOFULVENE CONJUGATES Illudent, Inc. (US) 2025-09-25 US disclosed
EP-4551241-A1 PRODRUGS OF CANNBIDIOL [CBD]-TYPE PHYTOCANNABINOIDS AND A PROCESS FOR PREPARATION THEREOF Council of Scientific & Industrial Research (IN) 2025-05-14 EP disclosed
US-12269793-B2 Affinity illudofulvene conjugates AF CHEMICALS, LLC (US) 2025-04-08 US disclosed
EP-3663291-B1 NUCLEAR TRANSPORT MODULATORS AND USES THEREOF KARYOPHARM THERAPEUTICS INC (US) 2024-12-18 EP disclosed
US-20240358710-A1 METHODS, COMPOSITIONS AND DEVICES FOR TREATING CANCER WITH ILLUDOFULVENES AF CHEMICALS, LLC (US) 2024-10-31 US disclosed
WO-2001001988-A1 COMPOUNDS HAVING CYTOKINE INHIBITORY ACTIVITY MERCK & CO., INC. (US) 2001-01-11 WO disclosed
US-5703075-A Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones PHARMACIA & UPJOHN COMPANY (US) 1997-12-30 US disclosed
EP-0525123-B1 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES UPJOHN CO (US) 1997-09-17 EP disclosed
US-5476934-A Oxidation a nitrogen-containing perfluoroacyl halide AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) 1995-12-19 US disclosed
US-5380844-A Nitrogen-containing perfluoroalkanoyl peroxide and method for production thereof AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) 1995-01-10 US disclosed
US-5347002-A Nitrogen-containing perfluoroalkanoyl peroxide and method for production thereof AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1994-09-13 US disclosed
US-5256825-A Promoter for fluoropolymer, heat exchanging AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1993-10-26 US disclosed
US-5208339-A Nitrogen-containing perfluoroalkanoyl peroxide and method for production thereof AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1993-05-04 US disclosed
EP-0525123-A1 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES. UPJOHN CO (US) 1993-02-03 EP disclosed
WO-1991019707-A2 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES THE UPJOHN COMPANY (US) 1991-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296912-A1 AFFINITY ILLUDOFULVENE CONJUGATES OGFR, TNFSF11, FCER2 KDM4E 1455/4885HSD17B10 4739/4885SMN1; SMN2 2596/4885
US-20260076982-A1 Prodrugs of Cannbidiol [CBD]-Type Phytocannabinoids and a Process for Preparation Thereof CNR1, CNR2, CBR1 KDM4E 2349/4885HSD17B10 208/4885SMN1; SMN2 1587/4885
US-20240358710-A1 METHODS, COMPOSITIONS AND DEVICES FOR TREATING CANCER WITH ILLUDOFULVENES MYC, MYCBP, TP53 KDM4E 3550/4885HSD17B10 4330/4885SMN1; SMN2 2152/4885
US-12269793-B2 Affinity illudofulvene conjugates OGFR, TNFSF11, FCER2 KDM4E 1455/4885HSD17B10 4739/4885SMN1; SMN2 2596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.