Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.49 |
| ▸ | PNP | P00491 | 2/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 7/20 | 0.48 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.48 |
| ▸ | KRAS | P01116 | 3/20 | 0.45 |
| ▸ | POLG | P54098 | 1/20 | 0.45 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410921 | 0.93 | TGM2 (0.55) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL14659959 | 0.89 | NT5E (0.51) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL407396 | 0.89 | NT5E (0.51) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL29093615 | 0.87 | NT5E (0.52) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL21105384 | 0.85 | POLB (0.53) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL30984597 | 0.85 | NT5E (0.48) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL3514475 | 0.85 | ADORA3 (0.48) | NT5EPNP | |
| SCHEMBL28993983 | 0.84 | NT5E (0.47) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL30984591 | 0.83 | TAS1R3 (0.47) | NT5EPOLBTGM2TAS1R3TAS1R1 | |
| SCHEMBL30984623 | 0.83 | NT5E (0.47) | NT5EPOLBTGM2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207891-A2 | MATERIALS AND METHODS FOR THE GENERATION OF TRANSCRIPTS COMPRISING MODIFIED NUCLEOTIDES | Archemix Corp. (US) | 2010-07-21 | — | — | EP | disclosed |
| WO-2008078180-A2 | MATERIALS AND METHODS FOR THE GENERATION OF TRANSCRIPTS COMPRISING MODIFIED NUCLEOTIDES | ARCHEMIX CORP. (US) | 2008-07-03 | — | — | WO | disclosed |