SCHEMBL28266552

SCHEMBL28266552

C=C(C)C(=O)OC.C=Cc1ccc(OC)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
MAPT P10636 3/20 0.50
CYP3A4 P08684 2/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX15 P16050 1/20 0.47
CYP2C19 P33261 1/20 0.47
GSK3B P49841 1/20 0.47
HDAC3 O15379 2/20 0.46
HDAC1 Q13547 2/20 0.46
HDAC2 Q92769 2/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
TGM2 P21980 1/20 0.46
F3 P13726 2/20 0.46
THRB P10828 1/20 0.45
ATM Q13315 1/20 0.45
CYP2A6 P11509 1/20 0.44
CYP1A2 P05177 1/20 0.44
PKM P14618 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7644030 0.91 ALDH1A1 (0.60) ALDH1A1MAPT
SCHEMBL28804590 0.85 ALDH1A1 (0.52) ALDH1A1MAPTCYP3A4CYP2C9CYP2C19
4-Vinylphenol SCHEMBL482393 0.85 ALDH1A1 (0.52) ALDH1A1MAPTTHRBPOLB
SCHEMBL29047980 0.83 ALDH1A1 (0.50) ALDH1A1MAPTCYP2C9CYP2C19TGM2
SCHEMBL29047981 0.83 ALDH1A1 (0.50) ALDH1A1MAPTCYP3A4CYP2C9CYP2C19
Styrene SCHEMBL8576362 0.83 ALDH1A1 (0.54) ALDH1A1MAPTPOLB
Styrene SCHEMBL35776 0.83 ALDH1A1 (0.54) ALDH1A1MAPTPOLB
Styrene SCHEMBL9182393 0.83 ALDH1A1 (0.54) ALDH1A1MAPTPOLB
Styrene SCHEMBL9639818 0.83 ALDH1A1 (0.54) ALDH1A1MAPTPOLB
Styrene SCHEMBL678464 0.83 ALDH1A1 (0.54) ALDH1A1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105384728-B Epoxy carboxylic acids' ester compounds and hardening thing containing its resin combination and the resin combination 日本化药株式会社 2018-12-21 CN disclosed