SCHEMBL28268449

SCHEMBL28268449

CCC(=O)NCc1ccc(O)c(C)c1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.52
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
ERCC1 P07992 7/20 0.49
ERCC4 Q92889 7/20 0.49
ALPG P10696 1/20 0.48
ALDH1A1 P00352 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
CYP2C19 P33261 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15290436 0.86 NR1H4 (0.50) TRPV1ALDH1A1HPGDALOX15
SCHEMBL1709342 0.86 TRPV1 (0.68) TRPV1ERCC1ERCC4
SCHEMBL14144815 0.85 ALDH1A1 (0.52) TRPV1ESR1ESR2ERCC1ERCC4
SCHEMBL16281310 0.85 ERCC1 (0.51) TRPV1ESR1ESR2ERCC1ERCC4
SCHEMBL14389115 0.84 TRPV1 (0.70) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL10411846 0.82 TRPV1 (0.80) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL23417762 0.82 TRPV1 (0.51) TRPV1ERCC1ERCC4
SCHEMBL20632696 0.82 HDAC1 (0.49) TRPV1ALDH1A1HPGDALOX15
SCHEMBL17205705 0.80 CYP1A2 (0.71) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL25558429 0.79 MMP13 (0.46) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109251621-A A kind of antifouling paint and preparation method thereof 山东陆邦涂料有限公司 2019-01-22 CN claimed