SCHEMBL17205705

SCHEMBL17205705

CCC(=O)NCc1ccc(O)c(OC)c1

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.71
CYP3A4 P08684 2/20 0.71
CYP2D6 P10635 2/20 0.71
CYP2C9 P11712 2/20 0.71
CYP2C19 P33261 2/20 0.71
BLM P54132 2/20 0.71
PMP22 Q01453 2/20 0.71
ALDH1A1 P00352 1/20 0.71
HPGD P15428 1/20 0.71
ALOX15 P16050 1/20 0.71
TRPV1 Q8NER1 7/20 0.67
MEN1 O00255 1/20 0.63
POLB P06746 1/20 0.63
TSHR P16473 1/20 0.63
KMT2A Q03164 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL906527 0.88 CYP1A2 (0.81) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL8168115 0.88 ALDH1A1 (0.67) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL7932225 0.87 CYP1A2 (0.66) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL24092698 0.87 CYP1A2 (0.66) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL3266072 0.86 HPGD (0.90) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5348698 0.85 CYP1A2 (0.90) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL15259678 0.85 HPGD (0.97) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL297477 0.84 ALDH1A1 (0.64) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5707095 0.84 MTNR1A (0.69) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL18517554 0.84 CYP1A2 (0.70) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015162216-A1 BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS UNIVERSITA' DEGLI STUDI DI SIENA (IT) 2015-10-29 WO claimed
US-20200157338-A1 SELF-POLISHING ZWITTERIONIC ANTI-FOULING RESIN HAVING MAIN CHAIN DEGRADABILITY AND PREPARATION THEREFOR AND USE THEREOF SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2020-05-21 US disclosed
CN-105839295-B A kind of preparation method of antibiotic fiber film 合肥市易远新材料有限公司 2019-04-30 CN disclosed
CN-105854643-A Antibacterial ultrafiltration membrane 安庆市天虹新型材料科技有限公司 2016-08-17 CN disclosed
WO-2015162216-A1 BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS UNIVERSITA' DEGLI STUDI DI SIENA (IT) 2015-10-29 WO disclosed