SCHEMBL28268460

SCHEMBL28268460

CC1CC(OC(=O)c2ccccc2C(=O)O)CC(C)(C)C1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.76
CYP3A4 P08684 3/20 0.76
CYP2C9 P11712 3/20 0.76
LMNA P02545 2/20 0.76
CYP2C19 P33261 2/20 0.76
CYP1A2 P05177 1/20 0.76
NR1I2 O75469 1/20 0.61
ABCB11 O95342 1/20 0.61
CYP2D6 P10635 2/20 0.51
TDP1 Q9NUW8 1/20 0.51
GAA P10253 1/20 0.43
ALOX15 P16050 2/20 0.40
SCN1A P35498 2/20 0.39
SCN2A Q99250 2/20 0.39
SCN3A Q9NY46 2/20 0.39
TSHR P16473 2/20 0.39
KDM4E B2RXH2 2/20 0.38
PTPRF P10586 1/20 0.38
PTPN2 P17706 1/20 0.38
PTPN1 P18031 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6905580 0.94 ALDH1A1 (0.84) ALDH1A1CYP3A4CYP2C9LMNACYP2C19
SCHEMBL3846508 0.94 ALDH1A1 (0.84) ALDH1A1CYP3A4CYP2C9LMNACYP2C19
SCHEMBL3846510 0.94 ALDH1A1 (0.84) ALDH1A1CYP3A4CYP2C9LMNACYP2C19
SCHEMBL3846512 0.94 ALDH1A1 (0.84) ALDH1A1CYP3A4CYP2C9LMNACYP2C19
SCHEMBL6908933 0.94 ALDH1A1 (0.84) ALDH1A1CYP3A4CYP2C9LMNACYP2C19
SCHEMBL6907927 0.94 ALDH1A1 (0.84) ALDH1A1CYP3A4CYP2C9LMNACYP2C19
Homosalate SCHEMBL2808104 0.88 ALDH1A1 (0.97) ALDH1A1CYP3A4CYP2C9LMNACYP2C19
Homosalate SCHEMBL3634890 0.86 ALDH1A1 (1.00) ALDH1A1CYP3A4CYP2C9LMNACYP2C19
Homosalate SCHEMBL29356436 0.86 ALDH1A1 (1.00) ALDH1A1CYP3A4CYP2C9LMNACYP2C19
Homosalate SCHEMBL16207 0.86 ALDH1A1 (1.00) ALDH1A1CYP3A4CYP2C9LMNACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106380729-B Novel PVC heat stabilizer 邵卫东 2019-01-29 CN disclosed
CN-106380729-A Novel PVC heat stablizer 邵卫东 2017-02-08 CN disclosed