Homosalate

Homosalate

SCHEMBL16207

CC1CC(OC(=O)c2ccccc2O)CC(C)(C)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
LMNA P02545 3/20 1.00
CYP3A4 P08684 3/20 1.00
CYP2C9 P11712 3/20 1.00
CYP2C19 P33261 2/20 1.00
CYP1A2 P05177 1/20 1.00
NR1I2 O75469 1/20 0.57
ABCB11 O95342 1/20 0.57
TSHR P16473 4/20 0.45
BCHE P06276 3/20 0.41
HSD17B10 Q99714 4/20 0.40
KDM4E B2RXH2 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
ALOX12 P18054 1/20 0.40
HTT P42858 1/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Homosalate SCHEMBL29356436 1.00 ALDH1A1 (1.00) ALDH1A1LMNACYP3A4CYP2C9CYP2C19
Homosalate SCHEMBL3634890 1.00 ALDH1A1 (1.00) ALDH1A1LMNACYP3A4CYP2C9CYP2C19
Homosalate SCHEMBL2808104 0.99 ALDH1A1 (0.97) ALDH1A1LMNACYP3A4CYP2C9CYP2C19
Homosalate SCHEMBL9452512 0.93 LMNA (0.86) ALDH1A1LMNACYP3A4CYP2C9CYP2C19
Homosalate SCHEMBL8840156 0.93 ALDH1A1 (0.86) ALDH1A1LMNACYP3A4CYP2C9CYP2C19
Homosalate SCHEMBL9452507 0.93 LMNA (0.86) ALDH1A1LMNACYP3A4CYP2C9CYP2C19
Homosalate SCHEMBL9099946 0.93 ALDH1A1 (0.86) ALDH1A1LMNACYP3A4CYP2C9CYP2C19
Homosalate SCHEMBL8106557 0.93 LMNA (0.86) ALDH1A1LMNACYP3A4CYP2C9CYP2C19
Homosalate SCHEMBL2016281 0.93 LMNA (0.86) ALDH1A1LMNACYP3A4CYP2C9CYP2C19
Homosalate SCHEMBL8863191 0.92 LMNA (0.84) ALDH1A1LMNACYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 30968 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144741-A1 NOVEL COMPOSITIONS DSM IP ASSETS B.V. (NL) 2026-05-28 US claimed
EP-4319884-B1 COSMETIC COMPOSITION COMPRISING HINOKITIOL UNILEVER IP HOLDINGS B V (NL) 2026-05-27 EP claimed
EP-4103144-B1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-05-27 EP claimed
CN-116456956-B Solid cosmetic material SHISEIDO CO.,LTD. (JP) 2026-05-26 CN claimed
CN-122075332-A Composition, preparation method thereof and sun-screening composition 2026-05-26 CN claimed
US-20260137611-A1 NOVEL COMPOSITIONS DSM IP ASSETS B V (NL) 2026-05-21 US claimed
WO-2026104139-A1 SUNSCREEN WITH HECTORITE BEIERSDORF AG (DE) 2026-05-21 WO claimed
WO-2026104140-A1 GLYCERYL STEARATE EMULSIFIERS IN COSMETIC EMULSIONS BEIERSDORF AG (DE) 2026-05-21 WO claimed
CN-122031293-A Efficient waterproof and sun-proof synergistic composition suitable for oil-in-water type and application thereof 诺斯贝尔化妆品股份有限公司 2026-05-15 CN claimed
WO-2026099270-A1 BIODEGRADABLE UV ABSORBERS AND USES THEREOF II BASF SE (DE) 2026-05-15 WO claimed
US-4613499-A Substituted cinnamal dialkyl malonates in sunscreening, skin care compositions VAN DYK & COMPANY INC. (US) 1986-09-23 US claimed
US-4603046-A TRI(HYDROXYALKYL)RUTOSIDE, HUMECTANTS CHARLES OF THE RITZ GROUP LTD. (US) 1986-07-29 US claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
US-4522807-A Substantive topical compositions PLOUGH, INC. (US) 1985-06-11 US claimed
US-4457911-A Dialkyl malonates as organic sunscreen adjuvants VAN DYK & COMPANY INC. (US) 1984-07-03 US claimed
EP-0100651-A1 Dialkyl malonates as organic suncreen adjuvants VAN DYK & COMPANY, INC. (US) 1984-02-15 EP claimed
EP-0085334-A2 Substantive topical compositions PLOUGH, INC. (a Delaware corporation) (US) 1983-08-10 EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-4150114-A ENHANCED PENETRATION THE PROCTER & GAMBLE COMPANY (US) 1979-04-17 US claimed
US-4001391-A USING AN OLEAGINOUS BASE CONTAINING FATS AND WAXES PLOUGH, INC. (US) 1977-01-04 US claimed