Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Homosalate SCHEMBL16207 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Homosalate SCHEMBL29356436 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Homosalate SCHEMBL2808104 | 0.99 | ALDH1A1 (0.97) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Homosalate SCHEMBL9452512 | 0.93 | LMNA (0.86) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Homosalate SCHEMBL8840156 | 0.93 | ALDH1A1 (0.86) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Homosalate SCHEMBL9452507 | 0.93 | LMNA (0.86) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Homosalate SCHEMBL9099946 | 0.93 | ALDH1A1 (0.86) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Homosalate SCHEMBL8106557 | 0.93 | LMNA (0.86) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Homosalate SCHEMBL2016281 | 0.93 | LMNA (0.86) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Homosalate SCHEMBL8863191 | 0.92 | LMNA (0.84) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9060943-B2 | Compositions comprising trans-tert-butyl cyclohexanol as skin irritation-reducing agent | SYMRISE AG (DE) | 2015-06-23 | — | — | US | disclosed |
| WO-2014149486-A1 | POLYMERS POLYMERIZED FROM AT LEAST FOUR MONOMERS, AND COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| EP-2701670-A1 | CLEAR WET SPRAYS AND GELS | Isp Investments Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2649033-A2 | COMPOSITIONS AND METHODS FOR STABILIZING INGREDIENTS USING 2,4-PENTANEDIONE COMPOUNDS | Sytheon Ltd. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012149355-A1 | CLEAR WET SPRAYS AND GELS | ISP INVESTMENTS INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012078546-A2 | COMPOSITIONS AND METHODS FOR STABILIZING INGREDIENTS USING 2,4-PENTANEDIONE COMPOUNDS | SYTHEON LTD. (US) | 2012-06-14 | — | — | WO | disclosed |
| US-20120121737-A1 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | SYMRISE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| EP-2144590-A1 | SKIN TREATMENT COMPOSITIONS AND METHODS | Sytheon Ltd. (US) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008140673-A1 | SKIN TREATMENT COMPOSITIONS AND METHODS | SYTHEON LTD. (US) | 2008-11-20 | — | — | WO | disclosed |
| EP-1811989-A1 | PREPARATION CONTAINING OXIDIZED FLAVONOID DERIVATIVES | Merck Patent GmbH (DE) | 2007-08-01 | — | — | EP | disclosed |
| US-6146617-A | A SUNSCREEN, SKIN CREAM OR GEL, HAIR GEL OR COSMETIC COMPOSITION MIXTURE COMPRISING A MICRONIZED METAL OXIDE, AND A LIQUID UV FILTER INCLUDING BENTONE, AEROSIL AND/OR ETHYLCELLULOSE | MERCK PATENT GESELLSCHAFT MIT (DE) | 2000-11-14 | — | — | US | disclosed |
| US-6143906-A | REACTING ASCORBIC ACID OR ASCORBIC ACID DERIVATIVES WITH SORBIC ACID OR SORBIC ACID DERIVATIVE TO FORM ASCORBYL SORBATES WHICH IS USED AS COSMETIC OR DURG | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-07 | — | — | US | disclosed |
| US-6090374-A | TREATING THE SKIN OR HAIR WITH EFFECTIVE AMOUNT OF ALPHA-STYRENE COMPOUND FOR PROTECTING THE HUMAN SKIN OR HAIR FROM ULTRAVIOLET RADIATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-18 | — | — | US | disclosed |
| US-6069258-A | SUNSCREEN AGENTS; PROTECTIVE COATINGS FOR SKIN | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-30 | — | — | US | disclosed |
| US-6007828-A | SUNSCREEN AGENT MIXTURE CONTAINING 1,1-DINITRILO-2,2-DIPHENYL ETHYLENE DERIVATIVE IN A COSMETIC CARRIER | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-28 | — | — | US | disclosed |
| US-5968484-A | APPLYING 2-ORGANOCARBONYLACRYLONITRILE DERIVATIVE AS SUNSCREEN AGENT | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-19 | — | — | US | disclosed |
| EP-0814760-A1 | SUBSTITUTED o-AMINOCARBONYLBENZOIC ACID SALTS AND THEIR USE AS SUNSCREENS | STEPAN COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5705169-A | REACTING FORMYLBENZALDEHYDE WITH KETOTRICYCLODECANE; DRUGS, COSMETICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-01-06 | — | — | US | disclosed |
| WO-1997025971-A1 | SUBSTITUTED o-AMINOCARBONYLBENZOIC ACID SALTS AND THEIR USE AS SUNSCREENS | STEPAN COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |
| US-5399563-A | Sunscreen agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121737-A1 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | TERT, CUTA, TRPA1 | ALDH1A1 1800/4885LMNA 1450/4885CYP3A4 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.