Sugi Predict

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Formic Acid

Formic Acid

SCHEMBL28268519

Clc1ccc(C2CCC2)cc1Cl.O=CO

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 9/20 0.54
▸ SLC6A4 P31645 9/20 0.54
▸ SLC6A3 Q01959 9/20 0.54
▸ KCNH2 Q12809 8/20 0.54
▸ CYP2D6 P10635 7/20 0.54
▸ ALDH1A1 P00352 1/20 0.42
▸ ACMSD Q8TDX5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2407 0.89 SLC6A2 (0.65) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL15335800 0.85 SLC6A2 (0.70) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL4331978 0.83 SLC6A2 (0.68) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL9870878 0.80 SLC6A2 (0.58) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
Formic Acid SCHEMBL27621842 0.79 HTR3A (0.48) ALDH1A1
SCHEMBL23420907 0.76 ACMSD (0.51) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL22817120 0.76 ESR2 (0.53) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL22817118 0.76 ESR2 (0.53) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL22817121 0.76 ESR2 (0.53) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
Formic Acid SCHEMBL28266835 0.75 USP30 (0.43) ACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109219602-A Modulators of cystic fibrosis transmembrane conductance regulator proteins 艾伯维公司 2019-01-15 — — CN disclosed