Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27682033 | 0.98 | NPC1 (0.52) | NOTUMNPC1RAB9APOLBAPAF1 | |
| SCHEMBL12906161 | 0.71 | NOTUM (0.59) | NOTUMKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL1799678 | 0.68 | ALDH1A1 (0.63) | NPC1RAB9APOLBAPAF1NSD2 | |
| SCHEMBL13528571 | 0.67 | NPC1 (1.00) | NPC1RAB9APOLBAPAF1NSD2 | |
| SCHEMBL17694561 | 0.67 | NOTUM (0.78) | NOTUMKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL9555 | 0.67 | NOTUM (1.00) | NOTUMNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2610163 | 0.66 | NOTUM (0.75) | NOTUMKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL13528568 | 0.66 | ALDH1A1 (0.68) | NPC1RAB9APOLBAPAF1NSD2 | |
| SCHEMBL1852694 | 0.65 | NPC1 (0.59) | NOTUMNPC1RAB9APOLBAPAF1 | |
| SCHEMBL2516355 | 0.65 | NPC1 (0.59) | NPC1RAB9APOLBAPAF1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206418-A | Using DMF as one step of carbon source construct 2-(2- furyl) -1,3,4- oxadiazoles method | 桂林理工大学 | 2019-01-15 | — | — | CN | disclosed |