Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 17/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993703 | 0.82 | KDM1A (0.57) | CHRNA7KDM1AMAOA | |
| SCHEMBL6993699 | 0.82 | KDM1A (0.57) | CHRNA7KDM1AMAOA | |
| SCHEMBL28268430 | 0.80 | CA2 (0.48) | CHRNA7CA12CA2CA9KDM1A | |
| SCHEMBL19378503 | 0.74 | CA12 (0.47) | CHRNA7CA12CA2CA9KDM1A | |
| SCHEMBL19378663 | 0.74 | FFAR1 (0.53) | CHRNA7CA12CA2CA9KDM1A | |
| SCHEMBL19378424 | 0.74 | CA2 (0.47) | CHRNA7CA12CA2CA9CA1 | |
| SCHEMBL18888959 | 0.74 | CA2 (0.47) | CHRNA7CA12CA2CA9KDM1A | |
| SCHEMBL7005093 | 0.74 | KDM1A (0.55) | CHRNA7CA12CA2CA9KDM1A | |
| SCHEMBL7005096 | 0.74 | KDM1A (0.55) | CHRNA7CA12CA2CA9KDM1A | |
| SCHEMBL18889026 | 0.74 | CA2 (0.47) | CHRNA7CA12CA2CA9KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153649-A | The allosteric modulators of nicotinic acetylcholine receptor | 默沙东公司 | 2019-01-04 | — | — | CN | disclosed |