Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 17/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005093 | 1.00 | KDM1A (0.55) | KDM1AMAOACA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL7093972 | 0.81 | KDM1A (0.58) | KDM1AMAOACA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL7093973 | 0.81 | KDM1A (0.58) | KDM1AMAOACA1CA2CA9 | |
| SCHEMBL6993703 | 0.76 | KDM1A (0.57) | KDM1AMAOACHRNA7 | |
| SCHEMBL6993699 | 0.76 | KDM1A (0.57) | KDM1AMAOACHRNA7 | |
| SCHEMBL28268539 | 0.74 | ALDH1A1 (0.51) | CA1CA2CA9CHRNA7CA12 | |
| SCHEMBL28270004 | 0.74 | CHRNA7 (0.48) | KDM1AMAOACA1CA2CA9 | |
| SCHEMBL28268430 | 0.74 | CA2 (0.48) | KDM1AMAOACA1CA2CA9 | |
| SCHEMBL14885503 | 0.72 | KDM1A (0.54) | KDM1AMAOA | |
| SCHEMBL21101247 | 0.72 | KDM1A (0.54) | KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097153-B1 | NOVEL TRIAZOLO[4,5-D]PYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | disclosed |