Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294561 | 0.88 | ACHE (0.44) | ACHESMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL14399304 | 0.87 | ACHE (0.56) | ACHEELANEESR1HIF1AKMT2A | |
| SCHEMBL29065053 | 0.86 | ACHE (0.41) | ACHEKMT2ALMNAALDH1A1GAA | |
| SCHEMBL28688122 | 0.86 | ACHE (0.55) | ACHEELANEESR1HIF1AKMT2A | |
| SCHEMBL10782553 | 0.82 | ACHE (0.71) | ACHEELANEESR1HIF1AKMT2A | |
| SCHEMBL14976794 | 0.81 | CYP3A4 (0.58) | ACHEKMT2ALMNADDB1CRBN | |
| SCHEMBL14159272 | 0.81 | LMNA (0.44) | ACHEKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11444965 | 0.81 | ACHE (0.69) | ACHEELANEESR1HIF1AKMT2A | |
| SCHEMBL1930874 | 0.80 | KMT2A (0.58) | ACHEELANEESR1HIF1AKMT2A | |
| SCHEMBL28329320 | 0.78 | GCK (0.40) | SMN1; SMN2ALDH1A1GAADDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483437-A | One kind is containing pentacyclic compound and its preparation and application | JIAXING WEIMOU BIOLOGICAL TECH CO LTD | 2019-11-22 | — | — | CN | disclosed |
| CN-109721605-A | A kind of immunocyte migrates inhibitor | 维眸生物科技（上海）有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-109134533-A | A kind of phosphorus-containing compound and its preparation and application | 维眸生物科技（上海）有限公司 | 2019-01-04 | — | — | CN | disclosed |