Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.39 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28018547 | 0.85 | GCK (0.40) | GCKAKR1C3AKR1C2KCNQ3KCNQ2 | |
| SCHEMBL12897604 | 0.80 | GCK (0.50) | GCKAKR1C3AKR1C2ALDH1A1GAA | |
| SCHEMBL14159272 | 0.79 | LMNA (0.44) | GCKAKR1C3AKR1C2ALDH1A1GAA | |
| SCHEMBL14976794 | 0.79 | CYP3A4 (0.58) | DDB1CRBNPTGS2 | |
| SCHEMBL28270688 | 0.78 | ACHE (0.56) | GCKALDH1A1GAADDB1CRBN | |
| SCHEMBL28270683 | 0.78 | ALDH1A1 (0.45) | KCNQ3KCNQ2KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL11991236 | 0.78 | CYP3A4 (0.61) | — | |
| SCHEMBL8784007 | 0.75 | THRB (0.41) | GCKAKR1C3AKR1C2ALDH1A1DDB1 | |
| SCHEMBL2294888 | 0.75 | ATM (0.58) | ALDH1A1GAA | |
| SCHEMBL16654619 | 0.74 | DDB1 (0.42) | GCKAKR1C3AKR1C2KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483437-A | One kind is containing pentacyclic compound and its preparation and application | JIAXING WEIMOU BIOLOGICAL TECH CO LTD | 2019-11-22 | — | — | CN | disclosed |