Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | AKT1 | P31749 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30873949 | 1.00 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL13731616 | 1.00 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL28271673 | 0.87 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL31667777 | 0.85 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL4526992 | 0.85 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL25852154 | 0.84 | KMT2A (0.59) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL7320870 | 0.83 | MEN1 (0.50) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL20538250 | 0.82 | ALDH1A1 (0.66) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL31068090 | 0.82 | ALDH1A1 (0.66) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL25934543 | 0.81 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1LMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843889-A | Spiral shell-lactams NMDA regulator and the method for using it | 阿普廷伊克斯股份有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-109415372-A | Spiral shell-lactams nmda receptor regulator and application thereof | 阿普廷伊克斯股份有限公司 | 2019-03-01 | — | — | CN | disclosed |