Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22268712 | 1.00 | OPRM1 (0.42) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL16992937 | 0.98 | OPRM1 (0.44) | OPRM1SPHK1LMNA | |
| SCHEMBL19300425 | 0.92 | OPRM1 (0.37) | OPRM1SPHK1LMNA | |
| SCHEMBL27676667 | 0.91 | OPRM1 (0.39) | OPRM1SPHK1LMNA | |
| SCHEMBL327325 | 0.91 | OPRM1 (0.39) | OPRM1SPHK1LMNA | |
| SCHEMBL9202942 | 0.91 | OPRM1 (0.39) | OPRM1SPHK1LMNA | |
| SCHEMBL9206536 | 0.91 | OPRM1 (0.39) | OPRM1SPHK1LMNA | |
| SCHEMBL11844847 | 0.90 | — | — | |
| SCHEMBL11804796 | 0.90 | GNAI3 (0.42) | OPRM1SPHK1 | |
| SCHEMBL21259255 | 0.90 | SHBG (0.45) | OPRM1SPHK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195621-A | Polynucleotides encoding interleukin 12(IL12) and uses thereof | 莫得纳特斯公司 | 2019-01-11 | — | — | CN | disclosed |