Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FGF23 | Q9GZV9 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011041 | 0.81 | MAOB (0.51) | MAOBTRPM8NFE2L2RELACA1 | |
| SCHEMBL30683539 | 0.81 | MAOB (0.51) | MAOBTRPM8NFE2L2RELACA1 | |
| SCHEMBL30987469 | 0.80 | MAOB (0.54) | MAOBNFE2L2NPC1MAPTKMT2A | |
| SCHEMBL255368 | 0.79 | MAOB (0.61) | MAOB | |
| SCHEMBL18648536 | 0.79 | APP (0.50) | MAOB | |
| SCHEMBL933856 | 0.79 | MAOA (0.51) | MAOB | |
| SCHEMBL164340 | 0.79 | MAOA (0.51) | MAOB | |
| SCHEMBL7055107 | 0.79 | TRPM8 (0.44) | MAOBTRPM8NFE2L2NPC1RAB9A | |
| SCHEMBL14329775 | 0.78 | RELA (0.67) | MAOBNFE2L2RELANPC1RAB9A | |
| SCHEMBL21018580 | 0.78 | MAOB (0.49) | MAOBTRPM8NFE2L2RELACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362140-A | Synthesis method of cyclohexyl substituted styrenes compound | 浙江工业大学 | 2024-01-09 | — | — | CN | disclosed |
| CN-109293468-B | Method for synthesizing cis-olefin through decarboxylation coupling reaction of NHP ester and terminal aryl alkyne under catalysis of iridium | 中南大学 | 2020-05-26 | — | — | CN | disclosed |
| CN-109293468-A | A method of it being catalyzed the decarboxylation coupling reaction synthesizing cis alkene of NHP ester and terminal aryl group alkynes by iridium | 中南大学 | 2019-02-01 | — | — | CN | disclosed |