Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006476 | 0.77 | MAPT (0.69) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL29139871 | 0.73 | KMT2A (0.54) | MAPTRAB9ANPC1LMNABCHE | |
| Chalcone SCHEMBL28767453 | 0.73 | CYP1B1 (0.69) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL29569445 | 0.72 | MAPT (0.62) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL5429856 | 0.72 | SNCA (0.62) | MAPTRAB9ANPC1HDAC3HDAC1 | |
| SCHEMBL18046509 | 0.72 | SNCA (0.62) | MAPTRAB9ANPC1HDAC3HDAC1 | |
| SCHEMBL11423417 | 0.71 | ALDH1A1 (0.34) | MAPTRAB9ASNCAMAPK1ALDH1A1 | |
| SCHEMBL29420130 | 0.71 | MAPT (0.75) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL626787 | 0.71 | MAPT (0.75) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL10893208 | 0.71 | MAPT (0.75) | MAPTRAB9ANPC1LMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232477-A | Chalcone-dithiocarbamates catalase-like inhibitor and its synthetic method and application | 郑州大学 | 2019-01-18 | — | — | CN | claimed |
| CN-109232477-A | Chalcone-dithiocarbamates catalase-like inhibitor and its synthetic method and application | 郑州大学 | 2019-01-18 | — | — | CN | disclosed |
| CN-109232477-A | Chalcone-dithiocarbamates catalase-like inhibitor and its synthetic method and application | 郑州大学 | 2019-01-18 | — | — | CN | disclosed |
| CN-109232477-A | Chalcone-dithiocarbamates catalase-like inhibitor and its synthetic method and application | 郑州大学 | 2019-01-18 | — | — | CN | disclosed |