Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405343 | 0.83 | LMNA (0.53) | KMT2AMAPTLMNAGAAALDH1A1 | |
| SCHEMBL1405342 | 0.83 | LMNA (0.53) | KMT2AMAPTLMNAGAAALDH1A1 | |
| SCHEMBL9006476 | 0.77 | MAPT (0.69) | KMT2AMAPTRAB9ANPC1LMNA | |
| SCHEMBL29960682 | 0.76 | HSD17B10 (0.50) | KMT2AMAPTRAB9ANPC1LMNA | |
| SCHEMBL28274147 | 0.73 | MAPT (0.49) | KMT2AMAPTRAB9ANPC1LMNA | |
| SCHEMBL9779620 | 0.73 | HDAC3 (0.57) | KMT2AMAPTRAB9ANPC1LMNA | |
| SCHEMBL9779623 | 0.73 | HDAC3 (0.57) | KMT2AMAPTRAB9ANPC1LMNA | |
| SCHEMBL398053 | 0.73 | KMT2A (0.49) | KMT2AGAAALDH1A1HPGDKDM4E | |
| SCHEMBL398055 | 0.73 | KMT2A (0.49) | KMT2AGAAALDH1A1HPGDKDM4E | |
| SCHEMBL1225684 | 0.73 | RAB9A (0.63) | KMT2AMAPTRAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229181-A | Preparation method of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2023-12-15 | — | — | CN | claimed |
| CN-117180248-A | Application of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2023-12-08 | — | — | CN | claimed |
| CN-117180248-B | Application of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2026-04-28 | — | — | CN | disclosed |
| CN-117180248-B | Application of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2026-04-28 | — | — | CN | disclosed |
| CN-117229181-B | Preparation method of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2025-08-01 | — | — | CN | disclosed |
| CN-117229181-B | Preparation method of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2025-08-01 | — | — | CN | disclosed |
| CN-117229181-A | Preparation method of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-117229181-A | Preparation method of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-117229181-A | Preparation method of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-117180248-A | Application of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-117180248-A | Application of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-117180248-A | Application of methylsulfonylamino chalcone derivative | 浙江工业大学 | 2023-12-08 | — | — | CN | disclosed |