Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796115 | 0.82 | REN (0.37) | MEN1KMT2AOPRD1SLC6A4SLC6A2 | |
| SCHEMBL27484196 | 0.80 | MEN1 (0.54) | MEN1KMT2AOPRD1SLC6A4SLC6A2 | |
| SCHEMBL13749719 | 0.79 | HRH3 (0.39) | HRH3SIGMAR1MEN1KMT2AOPRD1 | |
| SCHEMBL13749720 | 0.79 | HRH3 (0.39) | HRH3SIGMAR1MEN1KMT2AOPRD1 | |
| SCHEMBL4146000 | 0.76 | MEN1 (0.58) | HRH3MEN1KMT2AOPRD1SLC6A9 | |
| SCHEMBL2537196 | 0.76 | MEN1 (0.58) | HRH3MEN1KMT2AOPRD1SLC6A9 | |
| SCHEMBL2315253 | 0.76 | MEN1 (0.58) | HRH3MEN1KMT2AOPRD1SLC6A9 | |
| SCHEMBL27625371 | 0.76 | DPP4 (0.36) | HRH3SLC6A2SLC6A3KCNH2 | |
| SCHEMBL4099767 | 0.75 | CYP2D6 (0.56) | HRH3SIGMAR1MEN1KMT2AOPRD1 | |
| SCHEMBL4096152 | 0.75 | CYP2D6 (0.56) | HRH3SIGMAR1MEN1KMT2AOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311867-A | Conjugate comprising RIPK2 inhibitor | 葛兰素史克知识产权开发有限公司 | 2019-02-05 | — | — | CN | disclosed |