Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708283 | 0.82 | SLC1A2 (0.58) | LMNAHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27763275 | 0.77 | KMT2A (0.44) | LMNAHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27244159 | 0.77 | LMNA (0.58) | LMNAHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL28274372 | 0.77 | LMNA (0.58) | LMNAHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL20340201 | 0.76 | TDP1 (0.48) | LMNAHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL5137955 | 0.76 | TDP1 (0.48) | LMNAHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4689548 | 0.76 | SMN1; SMN2 (0.53) | LMNAHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL28458590 | 0.76 | SLC1A2 (0.51) | LMNAHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL14128517 | 0.76 | SLC1A2 (0.56) | LMNAHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4689551 | 0.76 | SMN1; SMN2 (0.53) | LMNAHPGDALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030072740-A1 | Pulmonary delivery of active agents | EMISPHERE TECHNOLOGIES, INC. | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030072740-A1 | Pulmonary delivery of active agents | ANXA11, ANXA1, PIGS | LMNA 1649/4885HPGD 1201/4885ALDH1A1 2109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.