Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27245273 | 0.87 | LMNA (0.62) | LMNAMAPK1HTTRAB9AMRGPRX4 | |
| SCHEMBL31258332 | 0.87 | LMNA (0.62) | LMNAMAPK1HTTRAB9AMRGPRX4 | |
| SCHEMBL28869415 | 0.85 | NOTUM (0.47) | HTTRAB9APARP10CXCL8P2RY14 | |
| SCHEMBL272042 | 0.85 | CA12 (0.57) | LMNAMAPK1HTTRAB9ATTR | |
| SCHEMBL16316825 | 0.83 | HTT (0.57) | LMNAHTTRAB9ATTR | |
| SCHEMBL2291665 | 0.81 | CHEK1 (0.60) | MAPK1HTTRAB9AP2RY14 | |
| SCHEMBL10148365 | 0.81 | TTR (0.69) | RAB9AMRGPRX4TTRLPAR1LPAR5 | |
| SCHEMBL26563555 | 0.80 | RXRA (0.56) | LMNAMAPK1HTTRAB9AMRGPRX4 | |
| SCHEMBL21156698 | 0.78 | P2RY14 (0.39) | PARP10CXCL8P2RY14LPAR1LPAR5 | |
| SCHEMBL22859971 | 0.76 | MAOB (0.46) | LMNAMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311860-A | For treating or preventing the Xanthone derivative of hepatitis type B virus disease | 豪夫迈·罗氏有限公司 | 2019-02-05 | — | — | CN | disclosed |