Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28275272 | 0.85 | LMNA (0.51) | PARP10P2RY14HTTRAB9ACXCL8 | |
| SCHEMBL27018576 | 0.82 | BRD4 (0.45) | NOTUMALDH1A1KMT2APYGLL3MBTL1 | |
| SCHEMBL14028926 | 0.82 | MGLL (0.46) | ALDH1A1KMT2AMGLLL3MBTL1MAPT | |
| SCHEMBL26563554 | 0.81 | CARM1 (0.50) | NOTUMALDH1A1KMT2AMGLLL3MBTL1 | |
| SCHEMBL8070206 | 0.81 | TTR (0.55) | NOTUMALDH1A1KMT2AMGLLL3MBTL1 | |
| SCHEMBL28276502 | 0.79 | PARP10 (0.67) | ALDH1A1KMT2APARP10L3MBTL1MAPT | |
| SCHEMBL23249875 | 0.77 | BRD4 (0.43) | ALDH1A1KMT2APYGLL3MBTL1MAPT | |
| SCHEMBL29890412 | 0.77 | BRD4 (0.43) | ALDH1A1KMT2APYGLL3MBTL1MAPT | |
| SCHEMBL12388479 | 0.77 | PDK2 (0.50) | NOTUMALDH1A1KMT2APYGLL3MBTL1 | |
| SCHEMBL2291665 | 0.76 | CHEK1 (0.60) | ALDH1A1KMT2AP2RY14NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311860-A | For treating or preventing the Xanthone derivative of hepatitis type B virus disease | 豪夫迈·罗氏有限公司 | 2019-02-05 | — | — | CN | disclosed |