SCHEMBL28275642

SCHEMBL28275642

CCOC(C(=O)ON1C(=O)CCC1=O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
GAA P10253 3/20 0.40
MMP8 P22894 1/20 0.38
SLC6A2 P23975 3/20 0.37
SLC6A3 Q01959 3/20 0.37
KDM4E B2RXH2 3/20 0.37
SLC6A4 P31645 2/20 0.37
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 2/20 0.36
ATM Q13315 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9030326 0.84 ALDH1A1 (0.41) GAAKDM4EALDH1A1KMT2AATM
SCHEMBL18206511 0.82 ALDH1A1 (0.51) TSHRGAAKDM4EALDH1A1KMT2A
SCHEMBL18206509 0.82 ALDH1A1 (0.51) TSHRGAAKDM4EALDH1A1KMT2A
SCHEMBL18207039 0.81 KLK7 (0.39) ALDH1A1KMT2AMEN1
SCHEMBL7379862 0.80 GAA (0.51) TSHRGAAKDM4EALDH1A1KMT2A
SCHEMBL7384133 0.80 GAA (0.51) TSHRGAAKDM4EALDH1A1KMT2A
SCHEMBL7381321 0.80 GAA (0.51) TSHRGAAKDM4EALDH1A1KMT2A
SCHEMBL18220935 0.79 GLS (0.38) ALDH1A1KMT2AATMMEN1
SCHEMBL18218927 0.78 ALDH1A1 (0.37) ALDH1A1KMT2AMEN1
SCHEMBL18207174 0.78 KMT2A (0.45) GAAALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109235048-A A kind of preparation method of fire-retardant air duct cloth material 孝感寰誉新材科技有限公司 2019-01-18 CN disclosed