Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | LTK | P29376 | 1/20 | 0.48 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL29355380 | 0.97 | MAOA (0.68) | MAOAKDM4ENPC1MAPTRAB9A | |
| Fluorene SCHEMBL545861 | 0.97 | MAOA (0.68) | MAOAKDM4ENPC1MAPTRAB9A | |
| Fluorene SCHEMBL29478468 | 0.97 | MAOA (0.68) | MAOAKDM4ENPC1MAPTRAB9A | |
| Fluorene SCHEMBL31388525 | 0.97 | MAOA (0.68) | MAOAKDM4ENPC1MAPTRAB9A | |
| Fluorene SCHEMBL8180 | 0.97 | MAOA (0.68) | MAOAKDM4ENPC1MAPTRAB9A | |
| Fluorene SCHEMBL10626727 | 0.93 | MAOA (0.65) | MAOAKDM4ENPC1MAPTRAB9A | |
| Fluorene SCHEMBL2432881 | 0.93 | MAOA (0.65) | MAOAKDM4ENPC1MAPTRAB9A | |
| Fluorene SCHEMBL9435671 | 0.93 | MAOA (0.65) | MAOAKDM4ENPC1MAPTRAB9A | |
| Fluorene SCHEMBL9791437 | 0.93 | MAOA (0.65) | MAOAKDM4ENPC1MAPTRAB9A | |
| Fluorene SCHEMBL1080516 | 0.93 | MAOA (0.65) | MAOAKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109251265-A | A kind of CGC type amine fluorenes rare-earth metal catalyst, preparation method and application | 北京理工大学 | 2019-01-22 | — | — | CN | disclosed |