SCHEMBL28275704

SCHEMBL28275704

O=c1nc[nH]c2c1ncn2CO

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
HSD17B10 Q99714 2/20 0.43
HPRT1 P00492 11/20 0.41
PNP P00491 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7147173 0.82 AHCY (0.45) ALDH1A1KDM4ETDP1HSD17B10HPRT1
SCHEMBL5616443 0.79 ALDH1A1 (0.44) ALDH1A1KDM4ETDP1HSD17B10HPRT1
SCHEMBL2639252 0.77 ALDH1A1 (0.37) ALDH1A1KDM4ETDP1HSD17B10HPRT1
SCHEMBL3306016 0.76 PNP (0.48) ALDH1A1KDM4ETDP1HSD17B10PNP
SCHEMBL7037922 0.76 ALDH1A1 (0.36) ALDH1A1KDM4ETDP1HSD17B10HPRT1
SCHEMBL25604284 0.75 HSD17B10 (0.39) ALDH1A1KDM4ETDP1HSD17B10HPRT1
SCHEMBL11270399 0.75 HSD17B10 (0.49) ALDH1A1KDM4ETDP1HSD17B10HPRT1
SCHEMBL28147771 0.74 ALDH1A1 (0.35) ALDH1A1KDM4ETDP1HSD17B10HPRT1
SCHEMBL7168417 0.73 ALDH1A1 (0.34) ALDH1A1KDM4ETDP1HSD17B10HPRT1
SCHEMBL612167 0.73 ALDH1A1 (0.34) ALDH1A1KDM4ETDP1HSD17B10HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109374768-A A kind of method of hypoxanthine content in measurement SHUXUETONG ZHUSHEYE 牡丹江友搏药业有限责任公司 2019-02-22 CN claimed
CN-109374768-A A kind of method of hypoxanthine content in measurement SHUXUETONG ZHUSHEYE 牡丹江友搏药业有限责任公司 2019-02-22 CN disclosed