SCHEMBL25604284

SCHEMBL25604284

CO[C@H](CO)CCn1cnc2c(=O)nc[nH]c21

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HPRT1 P00492 12/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
NFKB1 P19838 1/20 0.35
BLM P54132 1/20 0.35
VCP P55072 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35
PNP P00491 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23258833 1.00 HSD17B10 (0.39) HSD17B10ALDH1A1KDM4ETDP1HPRT1
SCHEMBL22847431 0.86 ALDH1A1 (0.35) HSD17B10ALDH1A1KDM4ETDP1HPRT1
SCHEMBL22781141 0.81 HPRT1 (0.55) HPRT1PNP
SCHEMBL22846919 0.78 LMNA (0.34) ALDH1A1MEN1LMNACYP3A4NFKB1
SCHEMBL28275704 0.75 ALDH1A1 (0.48) HSD17B10ALDH1A1KDM4ETDP1HPRT1
SCHEMBL7147173 0.74 AHCY (0.45) HSD17B10ALDH1A1KDM4ETDP1HPRT1
SCHEMBL25604296 0.71 MEN1 (0.30) ALDH1A1MEN1LMNACYP3A4NFKB1
SCHEMBL11270399 0.71 HSD17B10 (0.49) HSD17B10ALDH1A1KDM4ETDP1HPRT1
SCHEMBL18758938 0.71 BLM (0.68) HSD17B10ALDH1A1HPRT1MEN1LMNA
SCHEMBL454682 0.69 ALDH1A1 (0.71) HSD17B10ALDH1A1KDM4ETDP1HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230173079-A1 Conjugate Molecules DIVERSE BIOTECH, INC. (US) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230173079-A1 Conjugate Molecules CNR2, CNR1, MAG HSD17B10 3423/4885ALDH1A1 2054/4885KDM4E 1418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.