Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156635 | 0.92 | MEN1 (0.61) | MEN1KMT2AL3MBTL1POLBMAOA | |
| SCHEMBL31185843 | 0.90 | MEN1 (0.59) | MEN1KMT2AL3MBTL1POLBMAOA | |
| SCHEMBL1604003 | 0.83 | MEN1 (0.59) | MEN1KMT2AL3MBTL1POLBMAOA | |
| SCHEMBL2855789 | 0.81 | MEN1 (0.51) | MEN1KMT2AL3MBTL1POLBMAOA | |
| SCHEMBL19970698 | 0.80 | MEN1 (0.72) | MEN1KMT2AL3MBTL1POLBMAOA | |
| SCHEMBL27617262 | 0.74 | L3MBTL1 (0.50) | MEN1KMT2AL3MBTL1POLBMAOA | |
| SCHEMBL28057134 | 0.74 | ESR2 (0.51) | MEN1KMT2AL3MBTL1POLBMAOA | |
| SCHEMBL28864639 | 0.73 | MEN1 (0.67) | MEN1KMT2AL3MBTL1POLBLMNA | |
| SCHEMBL14035302 | 0.73 | MEN1 (0.50) | MEN1KMT2AL3MBTL1POLBMAOA | |
| SCHEMBL24916729 | 0.72 | ALOX5 (0.57) | MEN1KMT2AL3MBTL1POLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109320739-A | A kind of amphipathic alginate responded with light and pH and its stable pickering lotion | 海南大学 | 2019-02-12 | — | — | CN | disclosed |