SCHEMBL28276404

SCHEMBL28276404

CC(=O)N(C)C.CCCCCN

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.55
ALDH1A1 P00352 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
TSHR P16473 1/20 0.55
EPHX1 P07099 1/20 0.55
PAOX Q6QHF9 3/20 0.44
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
SIRT6 Q8N6T7 1/20 0.40
SIRT1 Q96EB6 1/20 0.40
GABBR2 O75899 1/20 0.40
GABRR1 P24046 1/20 0.40
GABBR1 Q9UBS5 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL1401909 0.85 DNM1 (0.67) DNM1ALDH1A1MEN1KMT2ATSHR
Octadecylamine SCHEMBL27966590 0.84 DNM1 (0.59) DNM1ALDH1A1MEN1KMT2ATSHR
Octadecylamine SCHEMBL27966591 0.84 DNM1 (0.59) DNM1ALDH1A1MEN1KMT2ATSHR
Dodecylamine SCHEMBL10615088 0.82 DNM1 (0.72) DNM1ALDH1A1MEN1KMT2ATSHR
Butanedione SCHEMBL27445424 0.82 DNM1 (0.63) DNM1ALDH1A1MEN1KMT2ATSHR
Octadecylamine SCHEMBL28874563 0.82 DNM1 (0.72) DNM1ALDH1A1MEN1KMT2ATSHR
Acetic Acid SCHEMBL3261104 0.82 DNM1 (0.63) DNM1ALDH1A1MEN1KMT2ATSHR
Hexadecylamine SCHEMBL28975320 0.82 DNM1 (0.72) DNM1ALDH1A1MEN1KMT2ATSHR
Tetradecylamine SCHEMBL28782763 0.81 DNM1 (0.62) DNM1ALDH1A1MEN1KMT2ATSHR
Acetic Acid SCHEMBL5487885 0.80 DNM1 (0.68) DNM1ALDH1A1MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109414454-A Combination treatment use for cancer treatment 加莱拉实验室有限责任公司 2019-03-01 CN disclosed