Acetone

Acetone

SCHEMBL1401909

CC(C)=O.CC(C)=O.CCCCCN

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.67
MEN1 O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
ALDH1A1 P00352 1/20 0.67
TSHR P16473 1/20 0.67
EPHX1 P07099 1/20 0.67
PAOX Q6QHF9 3/20 0.52
GABBR2 O75899 1/20 0.46
GABRR1 P24046 1/20 0.46
GABBR1 Q9UBS5 1/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
GNAI3 P08754 1/20 0.46
GNAO1 P09471 1/20 0.46
GNAI1 P63096 1/20 0.46
SIRT6 Q8N6T7 1/20 0.44
SIRT1 Q96EB6 1/20 0.44
AKR1B1 P15121 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexadecylamine SCHEMBL28975320 0.97 DNM1 (0.72) DNM1MEN1KMT2AALDH1A1TSHR
Dodecylamine SCHEMBL10615088 0.97 DNM1 (0.72) DNM1MEN1KMT2AALDH1A1TSHR
Octadecylamine SCHEMBL28874563 0.97 DNM1 (0.72) DNM1MEN1KMT2AALDH1A1TSHR
Butanedione SCHEMBL27445424 0.92 DNM1 (0.63) DNM1MEN1KMT2AALDH1A1TSHR
Acetic Acid SCHEMBL3261104 0.92 DNM1 (0.63) DNM1MEN1KMT2AALDH1A1TSHR
Butylamine SCHEMBL5320822 0.91
Tetradecylamine SCHEMBL609941 0.89 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
Acetic Acid SCHEMBL5487885 0.89 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
Hexadecylamine SCHEMBL325395 0.89 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
Octadecylamine SCHEMBL11524045 0.89 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180346629-A1 Biocompatible polymers and co-polymers, and uses thereof GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2018-12-06 US claimed
EP-2292672-B1 Biocompatible polymers and co-polymers comprising amino acids in the side chain CIS PHARMA AG (CH) 2018-05-09 EP claimed
US-20170152335-A1 Biocompatible polymers and co-polymers, and uses thereof HITZ HANS (CH) 2017-06-01 US claimed
EP-1888660-B1 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN CIS PHARMA AG (CH) 2017-05-17 EP claimed
US-8980957-B2 Methods for the preparation of biocompatible polymers, the polymers and their uses CIS PHARMA AG (CH) 2015-03-17 US claimed
US-20140242722-A1 ARTICLE AND METHOD FOR DETECTION OF A DRUG IN A LIQUID MEDIUM MEDTECH DETECT, LLC (US) 2014-08-28 US claimed
WO-2014062910-A1 SPIROPYRAN-BASED COLORIMETRIC DETECTION MEDTECH DETECT, LLC (US) 2014-04-24 WO claimed
US-20120329902-A1 METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES SCHAEFER ROLF (CH) 2012-12-27 US claimed
EP-2523982-A1 METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES Chemisches Institut Schaefer AG (CH) 2012-11-21 EP claimed
WO-2011085988-A1 METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES CHEMISCHES INSTITUT SCHAEFER AG (CH) 2011-07-21 WO claimed
EP-2292672-A2 Biocompatible polymers and co-polymers comprising amino acids in the side chain Chemisches Institut Schaefer AG (CH) 2011-03-09 EP claimed
US-20090232871-A1 Biocompatible polymers and co-polymers, and uses thereof HITZ HANS 2009-09-17 US claimed
EP-1888660-A2 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN Chemisches Institut Schaefer AG (CH) 2008-02-20 EP claimed
WO-2006126095-A2 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN CHEMISCHES INSTITUT SCHAEFER AG (CH) 2006-11-30 WO claimed
US-11008414-B2 Polymer materials for contact lens applications CIS PHARMA AG (CH) 2021-05-18 US disclosed
US-20200283560-A1 New polymer materials for contact lens applications CIS PHARMA AG (CH) 2020-09-10 US disclosed
EP-3356433-B1 NEW POLYMER MATERIALS FOR CONTACT LENS APPLICATIONS CIS PHARMA AG (CH) 2019-09-18 EP disclosed
US-20090232871-A1 Biocompatible polymers and co-polymers, and uses thereof HITZ HANS 2009-09-17 US disclosed
EP-1888660-A2 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN Chemisches Institut Schaefer AG (CH) 2008-02-20 EP disclosed
WO-2006126095-A2 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN CHEMISCHES INSTITUT SCHAEFER AG (CH) 2006-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090232871-A1 Biocompatible polymers and co-polymers, and uses thereof PPIH, ARG1, P4HA1 DNM1 4428/4885MEN1 3698/4885KMT2A 2241/4885
US-20170152335-A1 Biocompatible polymers and co-polymers, and uses thereof ARG1, CRYAA, COL1A1 DNM1 2059/4885MEN1 1846/4885KMT2A 3308/4885
US-20200283560-A1 New polymer materials for contact lens applications CRYAA, CRYAB, BCAT1 DNM1 2359/4885MEN1 3211/4885KMT2A 1532/4885
US-11008414-B2 Polymer materials for contact lens applications CRYAA, BCAT1, CRYAB DNM1 2426/4885MEN1 3234/4885KMT2A 1432/4885
US-20180346629-A1 Biocompatible polymers and co-polymers, and uses thereof ARG1, CRYAA, COL1A1 DNM1 2059/4885MEN1 1846/4885KMT2A 3308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.