Indoline

Indoline

SCHEMBL28278331

COC(=O)OC.c1ccc2c(c1)CCN2

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
MAPK1 P28482 1/20 0.43
MTNR1A P48039 3/20 0.42
MTNR1B P49286 1/20 0.42
DRD2 P14416 1/20 0.41
DRD4 P21917 1/20 0.41
PDPK1 O15530 1/20 0.41
PARP1 P09874 1/20 0.41
PARP10 Q53GL7 1/20 0.41
PARP11 Q9NR21 1/20 0.41
EPHX2 P34913 1/20 0.40
GFER P55789 1/20 0.40
BRD4 O60885 1/20 0.38
NPC1 O15118 1/20 0.38
MAPK13 O15264 1/20 0.38
MAPK12 P53778 1/20 0.38
MAPK11 Q15759 1/20 0.38
MAPK14 Q16539 1/20 0.38
SIRT2 Q8IXJ6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indoline SCHEMBL27915873 0.90 MEN1 (0.44) MEN1KMT2AMAPK1MTNR1AMTNR1B
Indoline SCHEMBL17652456 0.84 DRD2 (0.44) MEN1KMT2AMAPK1MTNR1AMTNR1B
Indoline SCHEMBL28078218 0.83 DRD2 (0.41) MEN1KMT2AMAPK1MTNR1AMTNR1B
Indoline SCHEMBL6769550 0.82 GFER (0.45) MEN1KMT2AMAPK1MTNR1AMTNR1B
Indoline SCHEMBL5120533 0.82 DRD2 (0.46) MEN1KMT2AMAPK1DRD2DRD4
Indoline SCHEMBL8003209 0.81 MAPK1 (0.40) MEN1KMT2AMAPK1MTNR1ADRD2
Indoline SCHEMBL29360339 0.81
Indoline SCHEMBL5629 0.81
Indoline SCHEMBL8922922 0.81 MAPK1 (0.40) MEN1KMT2AMAPK1MTNR1AMTNR1B
Indoline SCHEMBL28994086 0.81 PDPK1 (0.42) MEN1KMT2AMAPK1DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109475478-A Sunscreen compositions containing a combination of linear ultraviolet radiation absorbing polyethers and other ultraviolet screening compounds 强生消费者公司 2019-03-15 CN disclosed