SCHEMBL28278357

SCHEMBL28278357

CCC(Oc1ccccc1O)C(=O)NCc1cccs1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 6/20 0.52
▸ MAPT P10636 2/20 0.52
▸ TSHR P16473 2/20 0.50
▸ GAA P10253 2/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.47
▸ ALDH1A1 P00352 5/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ RAB9A P51151 2/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ POLB P06746 1/20 0.45
▸ LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28278385 0.87 HPGD (0.52) HPGDMAPTTSHRGAANPSR1
SCHEMBL28226958 0.86 TRPM8 (0.49) HPGDMAPTTSHRALDH1A1RAB9A
SCHEMBL28278345 0.81 HPGD (0.54) HPGDMAPTTSHRNPSR1ALDH1A1
SCHEMBL28194650 0.80 HPGD (0.59) HPGDMAPTTSHRGAANPSR1
SCHEMBL28277037 0.80 SMN1; SMN2 (0.59) HPGDMAPTTSHRALDH1A1RAB9A
SCHEMBL28277060 0.78 LMNA (0.56) HPGDMAPTTSHRNPSR1ALDH1A1
SCHEMBL28278483 0.77 HPGD (0.50) HPGDMAPTTSHRGAANPSR1
SCHEMBL10635025 0.77 HPGD (0.55) HPGDMAPTTSHRGAAALDH1A1
SCHEMBL10631746 0.76 HPGD (0.59) HPGDMAPTTSHRGAAALDH1A1
SCHEMBL21789034 0.72 RAB9A (0.53) HPGDMAPTTSHRGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109414048-A It is coated yeast formula 弗门尼舍有限公司 2019-03-01 — — CN disclosed
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