Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | C1S | P09871 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577709 | 0.84 | KDM4E (0.50) | KDM4EGAATDO2IKBKBADORA2A | |
| SCHEMBL4709256 | 0.84 | BCAT2 (0.59) | KDM4EGAAIKBKBSLC9A1PARP1 | |
| SCHEMBL28216055 | 0.82 | PRSS1 (0.52) | PRSS1PRSS2PRSS3KDM4EGAA | |
| SCHEMBL8887143 | 0.81 | GAA (0.59) | KDM4EGAAMAOBBRD4CDK4 | |
| SCHEMBL1515816 | 0.79 | GAA (0.62) | KDM4EGAAADORA2AADORA1MAOB | |
| SCHEMBL496484 | 0.79 | KDM4E (0.62) | KDM4EGAAALDH1A1LMNACYP2C8 | |
| SCHEMBL28216624 | 0.79 | MEN1 (0.48) | KDM4EGAAADORA2AADORA1ALDH1A1 | |
| SCHEMBL2020140 | 0.79 | ABL1 (0.59) | GAATDO2ADORA2AADORA1MAOB | |
| SCHEMBL28216187 | 0.79 | L3MBTL1 (0.47) | PRSS1PRSS2PRSS3ADORA2AADORA1 | |
| SCHEMBL7894667 | 0.78 | GAA (0.57) | KDM4EGAAMAOBBRD4CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109468659-A | The method of room temperature synthesizing benzimidazole under the conditions of electrocatalytic method water phase | 云南师范大学 | 2019-03-15 | — | — | CN | disclosed |
| CN-109456273-A | The method of benzenecarboximidamide class compound synthesis benzimidazole compound is used in microwave method water phase | 云南师范大学 | 2019-03-12 | — | — | CN | disclosed |