Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.95 |
| ▸ | GAA | P10253 | 5/20 | 0.95 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285846 | 0.97 | MAPT (1.00) | MAPTKDM4EGAAMCL1ALDH1A1 | |
| SCHEMBL28279 | 0.97 | MAPT (1.00) | MAPTKDM4EGAAMCL1ALDH1A1 | |
| SCHEMBL29363940 | 0.97 | MAPT (1.00) | MAPTKDM4EGAAMCL1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL9336609 | 0.95 | MAPT (0.95) | MAPTKDM4EGAAMCL1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL6838810 | 0.95 | MAPT (0.95) | MAPTKDM4EGAAMCL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9815129 | 0.95 | MAPT (0.95) | MAPTKDM4EGAAMCL1ALDH1A1 | |
| SCHEMBL1509347 | 0.90 | MAPT (0.85) | MAPTKDM4EGAAMCL1ALDH1A1 | |
| Formic Acid SCHEMBL7595259 | 0.84 | MAPT (0.75) | MAPTKDM4EGAAMCL1ALDH1A1 | |
| Phosphoric Acid SCHEMBL9139860 | 0.84 | MAPT (0.75) | MAPTKDM4EGAAMCL1ALDH1A1 | |
| SCHEMBL10258743 | 0.83 | GAA (0.74) | MAPTKDM4EGAAMCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800913-A | Geldanamycin derivatives and application thereof | 中国医学科学院药物研究所 | 2024-04-02 | — | — | CN | disclosed |