SCHEMBL1509347

SCHEMBL1509347

CN(C)c1cccc2ccc3cccc(N(C)C)c3c12

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.85
KDM4E B2RXH2 6/20 0.85
GAA P10253 5/20 0.85
ALDH1A1 P00352 9/20 0.50
TSHR P16473 6/20 0.50
HSD17B10 Q99714 5/20 0.50
HPGD P15428 4/20 0.50
CYP3A4 P08684 3/20 0.50
CYP1A2 P05177 2/20 0.50
MCL1 Q07820 1/20 0.50
CYP1A1 P04798 1/20 0.50
CYP1B1 Q16678 1/20 0.50
CNR2 P34972 1/20 0.41
THRB P10828 1/20 0.40
L3MBTL1 Q9Y468 4/20 0.39
TDP1 Q9NUW8 2/20 0.39
SIGMAR1 Q99720 1/20 0.39
TP53 P04637 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363940 0.92 MAPT (1.00) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL28279 0.92 MAPT (1.00) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL6285846 0.92 MAPT (1.00) MAPTKDM4EGAAALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL9336609 0.90 MAPT (0.95) MAPTKDM4EGAAALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL6838810 0.90 MAPT (0.95) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL30833304 0.90 MAPT (0.95) MAPTKDM4EGAAALDH1A1TSHR
Hydrochloric Acid SCHEMBL9815129 0.90 MAPT (0.95) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL10258743 0.83 GAA (0.74) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL8584145 0.81 KDM4E (0.71) MAPTKDM4EGAAALDH1A1TSHR
SCHEMBL22567091 0.81 MAPT (0.71) MAPTKDM4EGAAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5840056-A Iontophoresis electrode EMPI, INC. (US) 1998-11-24 US claimed
US-8361653-B2 Non-aqueous electrolyte secondary battery SHARP KABUSHIKI KAISHA (JP) 2013-01-29 US disclosed
US-20110052982-A1 NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY SHARP KABUSHIKI KAISHA (JP) 2011-03-03 US disclosed
US-7097789-B2 Thermoplastic containers exhibiting excellent protection to various ultraviolet susceptible compounds MILLIKEN & COMPANY (US) 2006-08-29 US disclosed
US-7094918-B2 Low-color ultraviolet absorbers for thermoplastic and thermoset high UV wavelength protection applications MILLIKEN & COMPANY (US) 2006-08-22 US disclosed
EP-1419347-B1 LOW-COLOR ULTRAVIOLET ABSORBERS FOR HIGH UV WAVELENGTH PROTECTION APPLICATIONS MILLIKEN & CO (US) 2006-06-14 EP disclosed
US-7014797-B2 Low-color ultraviolet absorbers for high UV wavelength protection applications MILLIKEN & COMPANY (US) 2006-03-21 US disclosed
WO-2005062733-A2 IMPROVED LOW-COLOR ULTRAVIOLET ABSORBERS FOR THERMOPLASTIC AND THERMOSET HIGH UV WAVELENGTH PROTECTION APPLICATIONS MILLIKEN & COMPANY (US) 2005-07-14 WO disclosed
US-6891058-B2 Low-color ultraviolet absorber compounds and compositions thereof MILLIKEN & COMPANY (US) 2005-05-10 US disclosed
EP-1419347-A4 LOW-COLOR ULTRAVIOLET ABSORBERS FOR HIGH UV WAVELENGTH PROTECTION APPLICATIONS MILLIKEN & CO (US) 2005-03-30 EP disclosed
US-6596795-B2 Liquids, permit use without the concomitant necessity of adding large amounts of other coloring agents to combat such discoloring MILLIKEN & COMPANY 2003-07-22 US disclosed
US-6559216-B1 To produce clear, ultraviolet radiation protected end products; permits use without the concomitant necessity of adding large amounts of other coloring agents to combat any discoloring within clear, colorless applications; efficiency MILLIKEN & COMPANY 2003-05-06 US disclosed
US-20030078329-A1 Low-color ultraviolet absorber compounds and compositions thereof MILLIKEN & COMPANY 2003-04-24 US disclosed
US-20030078326-A1 Low-color vanillin-based ultraviolet absorbers and methods of making thereof MILLIKEN & COMPANY 2003-04-24 US disclosed
US-20030075709-A1 Low-color ultraviolet absorbers for high UV wavelength protection applications MILLIKEN & COMPANY 2003-04-24 US disclosed
US-20030078328-A1 Low-color resorcinol-based ultraviolet absorbers and methods of making thereof MILLIKEN & COMPANY 2003-04-24 US disclosed
WO-2003019075-A1 LOW-COLOR ULTRAVIOLET ABSORBERS FOR HIGH UV WAVELENGTH PROTECTION APPLICATIONS MILLIKEN & COMPANY (US) 2003-03-06 WO disclosed
US-5840056-A Iontophoresis electrode EMPI, INC. (US) 1998-11-24 US disclosed
US-5788666-A Iontophoresis electrode EMPI, INC. (US) 1998-08-04 US disclosed
US-5419837-A Hindered amines for treating industrial water systems NALCO CHEMICAL COMPANY (US) 1995-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030078326-A1 Low-color vanillin-based ultraviolet absorbers and methods of making thereof VCL, VIM, MLN MAPT 2586/4885KDM4E 716/4885GAA 1323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.