Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279153 | 1.00 | MAPT (0.66) | MAPTL3MBTL1IDO1TP53THRB | |
| SCHEMBL27877588 | 0.90 | RAB9A (0.67) | MAPTIDO1ROCK2ROCK1RAB9A | |
| SCHEMBL21880164 | 0.90 | RAB9A (0.67) | MAPTIDO1ROCK2ROCK1RAB9A | |
| SCHEMBL21880165 | 0.90 | RAB9A (0.67) | MAPTIDO1ROCK2ROCK1RAB9A | |
| SCHEMBL30453904 | 0.90 | RAB9A (0.67) | MAPTIDO1ROCK2ROCK1RAB9A | |
| SCHEMBL6665555 | 0.88 | KMT2A (0.65) | MAPTL3MBTL1ROCK2ROCK1RAB9A | |
| SCHEMBL30452307 | 0.88 | KMT2A (0.65) | MAPTL3MBTL1ROCK2ROCK1RAB9A | |
| SCHEMBL7039856 | 0.85 | HDAC8 (0.66) | L3MBTL1RAB9AKMT2ANPC1HTT | |
| SCHEMBL8120133 | 0.83 | SLC7A5 (0.56) | ROCK2ROCK1KMT2AAAK1HDAC8 | |
| SCHEMBL30453040 | 0.82 | BACE1 (0.52) | IDO1TP53ROCK2ROCK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601734-B | Oximino naphthoquinone compound and preparation method and application thereof | 普济生物科技（台州）有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-112601734-A | Oximido naphthoquinone compound and preparation method and application thereof | 普济生物科技（台州）有限公司 | 2021-04-02 | — | — | CN | disclosed |
| CN-109438277-A | Oximido naphthoquinone compound and its preparation method and application | 普济生物科技（台州）有限公司 | 2019-03-08 | — | — | CN | disclosed |