Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30453904 | 1.00 | RAB9A (0.67) | RAB9AUSP2TSHRLMNACRHBP | |
| SCHEMBL21880164 | 1.00 | RAB9A (0.67) | RAB9AUSP2TSHRLMNACRHBP | |
| SCHEMBL27877588 | 1.00 | RAB9A (0.67) | RAB9AUSP2TSHRLMNACRHBP | |
| SCHEMBL28279155 | 0.90 | MAPT (0.66) | RAB9ANPC1ROCK2ROCK1POLB | |
| SCHEMBL28279153 | 0.90 | MAPT (0.66) | RAB9ANPC1ROCK2ROCK1POLB | |
| SCHEMBL7039856 | 0.85 | HDAC8 (0.66) | RAB9ANPC1POLBKMT2AALDH1A1 | |
| SCHEMBL6665555 | 0.85 | KMT2A (0.65) | RAB9AROCK2ROCK1KMT2AAAK1 | |
| SCHEMBL30452307 | 0.85 | KMT2A (0.65) | RAB9AROCK2ROCK1KMT2AAAK1 | |
| SCHEMBL9724920 | 0.85 | RAB9A (0.67) | RAB9AUSP2TSHRLMNACRHBP | |
| SCHEMBL7141131 | 0.84 | TSHR (0.60) | RAB9AUSP2TSHRNPC1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601734-B | Oximino naphthoquinone compound and preparation method and application thereof | 普济生物科技（台州）有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-112601734-A | Oximido naphthoquinone compound and preparation method and application thereof | 普济生物科技（台州）有限公司 | 2021-04-02 | — | — | CN | disclosed |
| WO-2020082817-A1 | NAPHTHOQUINONE OXIME COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 普济生物科技（台州）有限公司 | 2020-04-30 | — | — | WO | disclosed |
| CN-109438277-A | Oximido naphthoquinone compound and its preparation method and application | 普济生物科技（台州）有限公司 | 2019-03-08 | — | — | CN | disclosed |