Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | FPR2 | P25090 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 5/20 | 0.57 |
| ▸ | CIT | O14578 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | KLK7 | P49862 | 1/20 | 0.55 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665555 | 1.00 | KMT2A (0.65) | KMT2AL3MBTL1FPR2ALDH1A1MAPT | |
| SCHEMBL7039856 | 0.94 | HDAC8 (0.66) | KMT2AL3MBTL1FPR2ALDH1A1RAB9A | |
| SCHEMBL28974545 | 0.88 | GAA (0.63) | KMT2AALDH1A1MAPTHDAC8LTA4H | |
| SCHEMBL28279155 | 0.88 | MAPT (0.66) | KMT2AL3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28279153 | 0.88 | MAPT (0.66) | KMT2AL3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11120483 | 0.87 | RAB9A (0.59) | KMT2AL3MBTL1FPR2ALDH1A1MAPT | |
| SCHEMBL2994486 | 0.87 | BACE1 (0.57) | KMT2ARAB9ASMN1; SMN2HDAC8LTA4H | |
| SCHEMBL2994483 | 0.87 | BACE1 (0.57) | KMT2ARAB9ASMN1; SMN2HDAC8LTA4H | |
| SCHEMBL21880164 | 0.85 | RAB9A (0.67) | KMT2AALDH1A1MAPTRAB9AROCK2 | |
| SCHEMBL21880165 | 0.85 | RAB9A (0.67) | KMT2AALDH1A1MAPTRAB9AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601734-B | Oximino naphthoquinone compound and preparation method and application thereof | 普济生物科技（台州）有限公司 | 2023-05-23 | — | — | CN | disclosed |