Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.44 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280429 | 0.86 | CA2 (0.42) | ATAD2CECR2MEN1KMT2ACA9 | |
| SCHEMBL28280356 | 0.84 | KDM1A (0.41) | ATAD2CECR2CA9CA2CA12 | |
| SCHEMBL28280419 | 0.84 | IDH1 (0.44) | CA9CA2CA12CA1ALDH1A1 | |
| SCHEMBL29718834 | 0.84 | IDH1 (0.44) | CA9CA2CA12CA1ALDH1A1 | |
| SCHEMBL19551582 | 0.83 | CA12 (0.54) | MEN1HTTKMT2ACA9CA2 | |
| SCHEMBL19551605 | 0.82 | P2RX4 (0.55) | HTTCA9CA2CA12CA1 | |
| SCHEMBL19551459 | 0.81 | P2RX4 (0.47) | MEN1KMT2ACA9CA2CA12 | |
| SCHEMBL28280423 | 0.81 | P2RX4 (0.49) | MEN1KMT2ACA9CA2CA12 | |
| SCHEMBL19551533 | 0.81 | P2RX4 (0.56) | P2RX4 | |
| SCHEMBL19551724 | 0.81 | P2RX4 (0.50) | MEN1KMT2AP2RX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415321-A | aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2019-03-01 | — | — | CN | disclosed |