Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | BCR | P11274 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29718834 | 1.00 | IDH1 (0.44) | IDH1KIF11CA2CA9CA12 | |
| SCHEMBL28280429 | 0.86 | CA2 (0.42) | CA2CA9CA12CA1IDO1 | |
| SCHEMBL28279236 | 0.84 | ATAD2 (0.44) | CA2CA9CA12CA1MAPT | |
| SCHEMBL28280356 | 0.82 | KDM1A (0.41) | CA2CA9CA12CA1IDO1 | |
| SCHEMBL19551733 | 0.82 | P2RX4 (0.44) | CA2CA9CA12CA1KDM4E | |
| SCHEMBL19552576 | 0.82 | CA12 (0.50) | CA2CA9CA12CA1SMN1; SMN2 | |
| SCHEMBL29718681 | 0.82 | IDH1 (0.39) | IDH1KIF11MAPTKDM4EIDO1 | |
| SCHEMBL19551962 | 0.82 | P2RX4 (0.49) | ALDH1A1 | |
| SCHEMBL19551966 | 0.81 | P2RX4 (0.54) | CA2CA9CA12CA1MAPT | |
| SCHEMBL19551425 | 0.81 | CA12 (0.52) | CA2CA9CA12CA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415321-A | aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109415321-A | aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2019-03-01 | — | — | CN | disclosed |