Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22353067 | 0.85 | CA1 (0.34) | CA2CA12CA1CA9PGR | |
| SCHEMBL28280429 | 0.84 | CA2 (0.42) | IDO1CA2CA12CA1CA9 | |
| SCHEMBL28279236 | 0.84 | ATAD2 (0.44) | IDO1CA2CA12CA1CA9 | |
| SCHEMBL19551428 | 0.83 | P2RX4 (0.47) | ALDH1A1ENPP1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL29718834 | 0.82 | IDH1 (0.44) | IDO1CA2CA12CA1CA9 | |
| SCHEMBL28280419 | 0.82 | IDH1 (0.44) | IDO1CA2CA12CA1CA9 | |
| SCHEMBL28280449 | 0.82 | LMNA (0.43) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL19551485 | 0.82 | LMNA (0.40) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL19551645 | 0.82 | P2RX4 (0.49) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL19551617 | 0.81 | P2RX4 (0.46) | CA2CA12CA1CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415321-A | aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109415321-A | aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2019-03-01 | — | — | CN | disclosed |