SCHEMBL28279359

SCHEMBL28279359

CCCCCOC(=O)C(OC(=O)c1ccc(CCCC)cc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 2/20 0.47
ALDH1A1 P00352 3/20 0.46
POLB P06746 2/20 0.46
TRPV1 Q8NER1 1/20 0.45
TSHR P16473 2/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPK1 P28482 1/20 0.45
MAPT P10636 2/20 0.44
RARB P10826 2/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28279391 0.96 NPC1 (0.47) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL28551050 0.95 NPC1 (0.47) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL28279403 0.94 LMNA (0.48) NPC1RAB9ALMNAALDH1A1POLB
SCHEMBL28551059 0.93 ALDH1A1 (0.53) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL28278027 0.92 NPC1 (0.47) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL28278396 0.90 ALDH1A1 (0.50) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL28279357 0.90 NPC1 (0.53) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL28549109 0.89 ALDH1A1 (0.54) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL28548560 0.88 NPSR1 (0.54) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL28548555 0.87 NPC1 (0.48) NPC1RAB9ASMN1; SMN2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-109553712-A A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-A A kind of catalytic component and preparation method thereof for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed