SCHEMBL28279403

SCHEMBL28279403

CCCCc1ccc(C(=O)OC(C(=O)OCCC)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
ALDH1A1 P00352 5/20 0.47
POLB P06746 2/20 0.47
TRPV1 Q8NER1 1/20 0.46
RARB P10826 2/20 0.45
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 2/20 0.42
MAPK1 P28482 1/20 0.42
UBE2N P61088 1/20 0.42
PLK1 P53350 1/20 0.42
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28279391 0.95 NPC1 (0.47) LMNAALDH1A1POLBTRPV1RARB
SCHEMBL28279359 0.94 NPC1 (0.47) LMNAALDH1A1POLBTRPV1RARB
SCHEMBL28548556 0.93 LMNA (0.50) LMNAALDH1A1POLBMAPTMEN1
SCHEMBL28278396 0.91 ALDH1A1 (0.50) LMNAALDH1A1POLBTRPV1RARB
SCHEMBL28278027 0.90 NPC1 (0.47) LMNAALDH1A1POLBTRPV1MAPT
SCHEMBL28277995 0.90 ALDH1A1 (0.56) LMNAALDH1A1POLBMAPTMEN1
SCHEMBL28551050 0.89 NPC1 (0.47) LMNAALDH1A1POLBMAPTMEN1
SCHEMBL28541985 0.88 CYP4F2 (0.50) LMNAALDH1A1POLBTRPV1RARB
SCHEMBL28549109 0.88 ALDH1A1 (0.54) LMNAALDH1A1POLBMAPTMEN1
SCHEMBL28277999 0.87 LMNA (0.63) LMNAALDH1A1POLBMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-109553712-A A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-A A kind of catalytic component and preparation method thereof for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed
CN-109553712-A A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN disclosed
CN-109553705-A A kind of catalytic component and preparation method thereof for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN disclosed