SCHEMBL28279368

SCHEMBL28279368

CC(CC(=O)Oc1ccccc1)OC(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
POLB P06746 1/20 0.48
SCN1A P35498 1/20 0.48
SCN2A Q99250 1/20 0.48
SCN3A Q9NY46 1/20 0.48
NPC1 O15118 2/20 0.47
ELANE P08246 2/20 0.46
TSHR P16473 2/20 0.46
TP53 P04637 1/20 0.46
PDCD1 Q15116 1/20 0.45
CD274 Q9NZQ7 1/20 0.45
ALDH1A1 P00352 3/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MAPT P10636 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28278496 0.85 LMNA (0.46) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL5082895 0.84 PDCD1 (0.56) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL29302944 0.84 LMNA (0.54) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL5082911 0.84 LMNA (0.54) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL28278035 0.82 ELANE (0.48) LMNAELANETSHRTP53PDCD1
SCHEMBL5082899 0.82 LMNA (0.54) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL888349 0.81 NPC1 (0.50) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL28279397 0.80 ALDH1A1 (0.47) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL15869129 0.80 LMNA (0.52) LMNACYP1A2CYP2D6POLBSCN1A
SCHEMBL28454790 0.80 ELANE (0.44) LMNAPOLBNPC1ELANETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-109553712-A A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-A A kind of catalytic component and preparation method thereof for olefinic polymerization 中国石油化工股份有限公司 2019-04-02 CN claimed
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed